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Home » Meals » Lunch & Dinner » Cheesy Spaghetti Tetrazzini

Cheesy Spaghetti Tetrazzini

August 13, 20208 Comments

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Cheesy Spaghetti Tetrazzini is baked until bubbly with a creamy sauce, mushrooms, and plenty of melted cheese. See the recipe card for step-by-step instructions on how to make this classic comfort food casserole. via @thiswifecooks

Cheesy Spaghetti Tetrazzini is a creamy casserole made with spaghetti, mushrooms, and plenty of cheese. Serve with toasted garlic bread and a Garden Kale Salad.

Easy Cheesy Tetrazzini side view in a shallow white serving bowl. Yellow cheddar cheese, mushrooms, and black pepper visible.

Table of Contents

Toggle
  • Easy Comfort Food
  • Ingredients for Cheesy Spaghetti Tetrazzini
  • How to Make Easy Cheesy Tetrazzini:
  • Make It Vegan 🌱
  • More Comfort Food Recipes You’ll Love!
  • Cheesy Spaghetti Tetrazzini Recipe
    • Ingredients
    • Instructions
    • Nutrition

Easy Comfort Food

Tetrazzini is one of those cozy, old-school casseroles that hits the spot when you’re craving something creamy and filling. Traditionally made with spaghetti and a creamy sauce, it’s baked with a good amount of cheese until bubbly and golden on top.

It’s simple, comforting, and feeds a crowd.

Easy Cheesy Tetrazzini close-up with creamy sauce, cheddar cheese, pieces of mushroom, and flecks of ground black pepper.

Ingredients for Cheesy Spaghetti Tetrazzini

You will need the following:

  • Spaghetti – Spaghetti is the most traditional pasta shape for this dish but other long pastas, including linguine and fettuccine, also work well.
  • Butter, Onion & Mushrooms – Sautéed together to add a savory, flavorful base to the sauce.
  • Evaporated Milk & Cream-Style Soup – These combine to form a rich and creamy sauce.
  • Cheese – Shredded cheddar and Colby Jack are melted into the sauce and sprinkled over the top. Mozzarella or Monterey Jack are both good in this dish, too.
  • Seasoning Blends – Montreal Chicken Seasoning, which happens to be vegan, and celery salt give the casserole its classic flavor profile.
Easy Cheesy Tetrazzini is shown with a fork twirling a bite.

Serving of Easy Cheesy Tetrazzini in white bowl in front of filled casserole dish with remaining pasta.

How to Make Easy Cheesy Tetrazzini:

STEP ONE: Prep. Preheat the oven to 350°F. Spray a 9×13-inch baking dish with non-stick cooking spray.

STEP TWO: Cook the Pasta. Cook spaghetti according to package directions. Rinse with cold water, drain, and return to the cooking pot.

STEP THREE: Make the Sauce. Into a large saucepan over medium-high heat, add the butter. When the butter is melted, add the onion and mushrooms. Cook, stirring frequently for 3 minutes, until softened. Add the evaporated milk, cream of mushroom soup, cheddar cheese, Montreal Chicken seasoning, celery salt, salt, and ground black pepper. Stir to combine. Adjust seasoning to taste.

STEP FOUR: Combine Pasta and Sauce. Pour the sauce over the spaghetti. Toss to distribute the sauce throughout evenly. The mixture will be very soupy. Transfer the pasta to the prepared 9×13-inch baking dish. Sprinkle Colby-Jack cheese over the top.

STEP FIVE: Bake and Serve. Bake, uncovered, for 40 minutes. Serve hot.

Make It Vegan 🌱

Swap in your favorite plant-based cheeses, butter, evaporated milk, and cream-style soup.

Vegan Evaporated Milk – Look for dairy-free evaporated milk on the baking aisle or in the vegan specialty section of your supermarket. If it’s not available in your area, try homemade Vegan Evaporated Milk. The recipe yields the equivalent of one 12-ounce can so it needs to be doubled for this recipe. It does also need a bit of simmer time so plan accordingly.

Vegan Cream-Style Soup – I use my own recipes for Vegan Cream of Mushroom and Vegan Cream of Chicken Substitute (Both work well for this dish; the cream of chicken is a little more economical.) They each yield the equivalent of one can of condensed soup so be sure to double to get the 20 ounces needed for this recipe.

Top down view of cheesy spaghetti casserole, hot out of the oven.

More Comfort Food Recipes You’ll Love!

  • Crockpot Cheesy Potatoes
  • Creamy Vegan Mac and Cheese
  • Vegan Salisbury Steak with Mushroom Gravy
  • Baked Pesto Pasta Casserole

Save this recipe to Pinterest! ⤵️ 📌

Two white bowls filled with creamy, easy cheesy tetrazzini. A fork lifts a portion of the cheesy pasta in the top image. Text reads Easy Cheesy Tetrazzini and thiswifecooks.com on a brown banner between the images.
Easy Cheesy Tetrazzini ~ Spaghetti pasta tossed in a rich and creamy, dairy-free cheese sauce then baked for an ultra comforting casserole the whole family will love. This kid-friendly pasta bake is ready to serve in about an hour.

Cheesy Spaghetti Tetrazzini Recipe

Spaghetti baked in a rich and creamy, dairy-free cheesy sauce for an easy, ultra comforting casserole.
5 from 12 votes
Print Pin Rate
Course: Main Course
Cuisine: American, Italian
Keyword: casserole, comfort food, pasta, spaghetti, tetrazzini, vegetarian, vegetarian appetizer
Prep Time: 10 minutes minutes
Cook Time: 50 minutes minutes
Total Time: 1 hour hour
Servings: 6
Calories: 661kcal
Author: Holly Gray
Prevent your screen from going dark

Ingredients

  • 16 ounces spaghetti
  • 1 tablespoon butter
  • 1/2 cup yellow onion chopped
  • 1/2 cup cremini mushrooms thinly sliced
  • 24 ounces evaporated milk
  • 20 ounces condensed cream of mushroon soup
  • 8 ounces cheddar cheese shredded
  • 1 tablespoon Montreal Chicken seasoning blend
  • 1 teaspoon celery salt
  • 1/2 teaspoon koshersalt
  • 1/2 teaspoon ground black pepper
  • 4 ounces Colby-Jack cheese shredded

Instructions

  • Preheat the oven to 350°F. Spray a 9×13-inch baking dish with non-stick cooking spray.
  • Cook spaghetti according to package directions. Rinse with cold water, drain, and return to the cooking pot.
  • Into a large saucepan over medium-high heat, add the butter. When the butter is melted, add the onion and mushrooms. Cook, stirring frequently for 3 minutes, until softened. Add the evaporated milk, cream of mushroom, cheddar cheese, Montreal Chicken seasoning, celery salt, salt, and ground black pepper. Stir to combine. Adjust seasoning to taste
  • Pour the sauce over the spaghetti. Toss to evenly distribute the sauce throughout. The mixture will be very soupy. Transfer the pasta to the prepared 9×13-inch baking dish. Sprinkle Colby-Jack cheese over the top.
  • Bake, uncovered for 40 minutes then serve hot.

Nutrition

Calories: 661kcal | Carbohydrates: 86g | Protein: 21g | Fat: 25g | Saturated Fat: 10g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 5g | Trans Fat: 0.01g | Cholesterol: 40mg | Sodium: 1763mg | Potassium: 608mg | Fiber: 4g | Sugar: 15g | Vitamin A: 533IU | Vitamin C: 3mg | Calcium: 357mg | Iron: 3mg
Tried this recipe?Mention @thiswifecooks or tag #thiswifecooks!

This post was updated on July 25, 2025.

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Filed Under: Casseroles, Comfort Food, Lunch & Dinner, Pasta Night, Recently Updated, Vegan, Vegetarian Tagged With: casserole, comfort food, pasta, spaghetti

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Reader Interactions

Comments

  1. Chris

    April 11, 2022 at 3:02 pm

    5 stars
    What a delicious pasta recipe! This tetrazzini was so creamy. I prefer these over traditional mac and cheese!

    Reply
  2. Kayla DiMaggio

    April 11, 2022 at 5:00 pm

    5 stars
    This cheesy tetrazzini was so delicious! You couldn’t event tell it was vegan!

    Reply
  3. Jacqui

    April 11, 2022 at 9:38 pm

    5 stars
    This is another fantastic recipe from Holly! It is so delicious and you can’t even tell it’s dairy free – tastes so creamy and cheesy.

    Reply
  4. Emily

    April 11, 2022 at 11:06 pm

    5 stars
    The recipe name is fun to say, and it’s even more fun to eat! This pasta dish was a home run for the whole family!

    Reply
  5. nancy

    April 12, 2022 at 6:22 pm

    5 stars
    you are right about it being kid friendly. i think DD polished it off before hubby and I got to it

    Reply
  6. Anaiah

    April 12, 2022 at 9:46 pm

    5 stars
    Such a creamy and delicious pasta recipe. It’s great with breaded tofu and even a side of veggies, but I could eat it all on its own too.

    Reply
  7. Keri

    April 13, 2022 at 10:38 am

    5 stars
    Our family loved easy cheesy tetrazzini! It was so rich and creamy and satisfying!

    Reply
  8. Katie

    April 13, 2022 at 11:12 am

    5 stars
    This recipe is incredibly creamy and delicious! Perfect for serving to non vegans, they won’t even notice it’s vegan!

    Reply
5 from 12 votes (4 ratings without comment)

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