Preheat the oven to 425°F. Line a sheet pan with parchment paper.
Place cauliflower florets in a large bowl and set aside.
In a small bowl, whisk together the olive oil, white wine vinegar, fresh sage, garlic, salt, and black pepper. Adjust seasoning to taste.
Pour the olive oil mixture over the cauliflower florets and toss to coat.
Transfer cauliflower mixture to the prepared baking sheet and spread in a single layer.
Roast in the preheated oven for 20 minutes, stirring halfway through the cooking time, until the cauliflower is golden brown. Serve hot.